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Pfizer Inc

Exchange: NYSESector: HealthcareIndustry: Drug Manufacturers - General

At Pfizer Oncology, we are at the forefront of a new era in cancer care. Our industry-leading portfolio and extensive pipeline includes three core mechanisms of action to attack cancer from multiple angles, including small molecules, antibody-drug conjugates (ADCs), and multispecific antibodies, including other immune-oncology biologics. We are focused on delivering transformative therapies in some of the world's most common cancers, including breast cancer, gastrointestinal cancer, genitourinary cancer, hematology-oncology, and thoracic cancers, which includes lung cancer. Driven by science, we are committed to accelerating breakthroughs to help people with cancer live better and longer lives. About the Pfizer, Astellas and Merck Collaboration Seagen and Astellas entered a clinical collaboration agreement with Merck to evaluate the combination of Seagen's and Astellas' PADCEV™ (enfortumab vedotin) and Merck's Keytruda ® (pembrolizumab) in patients with muscle-invasive bladder cancer (MIBC) who are eligible for cisplatin-based chemotherapy. Seagen and Astellas entered a clinical collaboration agreement with Merck to evaluate the combination of Seagen's and Astellas' PADCEV™ (enfortumab vedotin) and Merck's Keytruda ® (pembrolizumab) in patients with muscle-invasive bladder cancer (MIBC) who are eligible for cisplatin-based chemotherapy. Pfizer Inc. successfully completed its acquisition of Seagen on December 14, 2023. Keytruda is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside of the United States and Canada).

Did you know?

Free cash flow has been growing at -2.5% annually.

Current Price

$26.67

-0.49%

GoodMoat Value

$17.95

32.7% overvalued
Profile
Valuation (TTM)
Market Cap$151.64B
P/E19.52
EV$203.41B
P/B1.75
Shares Out5.69B
P/Sales2.42
Revenue$62.58B
EV/EBITDA14.39

Pfizer Inc (PFE) Stock Analysis

GoodMoat Analysis

Based on data as of March 26, 2026

Pfizer is a global pharmaceutical giant facing a post-pandemic transition, with its moat primarily based on patents and scale. The stock trades at a significant premium to the GoodMoat target price, indicating an unfavourable valuation. The combination of a weak moat score and high valuation suggests it fails the initial gates of the investment framework.

Read full analysis
Pfizer Inc. is a global pharmaceutical leader that discovers, develops, and commercializes medicines and vaccines, most notably its COVID-19 products. Its primary competitive advantages, assessed through the GoodMoat framework, are likely in Regulatory Barriers (patents) and Scale Privilege in manufacturing and R&D. However, the company scores poorly on other moat criteria such as Low Disruption Risk, Pricing Power in the face of generic competition, and Network Effects. With a likely Moat Score below the critical threshold of 5, it fails the first gate of the Decision Framework. Financially, the company shows strain with a -1.2% YoY revenue decline, a 12.4% profit margin, and an ROE of 9.0%, which is below the 15-20% high-quality benchmark. While the dividend yield of 6.30% is high, the valuation is a key concern. The current price of $27.44 is approximately 53% above the GoodMoat target of $17.95, suggesting a deeply unfavourable margin of safety. This significant overvaluation, combined with the weak underlying business quality and growth trajectory, makes further investigation from a traditional value perspective unfavourable unless a compelling thesis for a durable post-COVID turnaround emerges.

PFE Price Chart

Market Cap$151.64B
Current Price$26.67
P/E Ratio19.52
Forward P/E
PEG Ratio-0.04
EPS$1.36
Book Value$15.21
P/B Ratio1.75

PFE Financial Charts

FCF vs CAPEX

FCFCAPEX

Forward estimates use -2.5% FCF growth (CAGR)

Cash vs Debt

Net Debt: 63.7B

Revenue

40.9B

FY19

41.7B

FY20

81.3B

FY21

101.2B

FY22

59.6B

FY23

63.6B

FY24

62.6B

FY25

Net Income

16.0B

FY19

9.2B

FY20

22.0B

FY21

31.4B

FY22

2.1B

FY23

8.0B

FY24

7.8B

FY25

PFE 52-Week Range

$20.92
$28.55
50-Day MA: $27.23200-Day MA: $25.16
Did you know?

Free cash flow has been growing at -2.5% annually.

Pfizer Inc (PFE) Financial Summary

Pfizer Inc (PFE) is a Healthcare company in the Drug Manufacturers - General industry, listed on NYSE. The stock currently trades at $26.67 with a market capitalization of $151.64B.

Key valuation metrics include a P/E ratio of 19.52, price-to-book ratio of 1.75, and EPS of $1.36. The company reports a profit margin of 12.4% and return on equity of 9.0%.

PFE Key Financial Metrics

MetricValue
Market Cap$151.64B
P/E Ratio19.52
EPS$1.36
P/B Ratio1.75
P/S Ratio2.42
EV/EBITDA14.39
Dividend Yield6.44%
Profit Margin12.4%
Return on Equity9.0%
Debt/Equity0.75

PFE Revenue & Earnings History

YearRevenueNet Income
FY19$40.91B$16.03B
FY20$41.65B$9.16B
FY21$81.29B$21.98B
FY22$101.17B$31.37B
FY23$59.55B$2.12B
FY24$63.63B$8.03B
FY25$62.58B$7.77B

Pfizer Inc (PFE) Valuation

Based on GoodMoat's DCF model, Pfizer Inc has a fair value estimate of $17.95. At the current price of $26.67, the stock appears 48.5% overvalued relative to our intrinsic value estimate.

PFE Quality Indicators

Pfizer Inc maintains a profit margin of 12.4% and an operating margin of 12.0%. Return on equity stands at 9.0%. The current ratio is 1.16. Debt-to-equity ratio is 0.75.

About Pfizer Inc

At Pfizer Oncology, we are at the forefront of a new era in cancer care. Our industry-leading portfolio and extensive pipeline includes three core mechanisms of action to attack cancer from multiple angles, including small molecules, antibody-drug conjugates (ADCs), and multispecific antibodies, including other immune-oncology biologics. We are focused on delivering transformative therapies in some of the world's most common cancers, including breast cancer, gastrointestinal cancer, genitourinary cancer, hematology-oncology, and thoracic cancers, which includes lung cancer. Driven by science, we are committed to accelerating breakthroughs to help people with cancer live better and longer lives. About the Pfizer, Astellas and Merck Collaboration Seagen and Astellas entered a clinical collaboration agreement with Merck to evaluate the combination of Seagen's and Astellas' PADCEV™ (enfortumab vedotin) and Merck's Keytruda ® (pembrolizumab) in patients with muscle-invasive bladder cancer (MIBC) who are eligible for cisplatin-based chemotherapy. Seagen and Astellas entered a clinical collaboration agreement with Merck to evaluate the combination of Seagen's and Astellas' PADCEV™ (enfortumab vedotin) and Merck's Keytruda ® (pembrolizumab) in patients with muscle-invasive bladder cancer (MIBC) who are eligible for cisplatin-based chemotherapy. Pfizer Inc. successfully completed its acquisition of Seagen on December 14, 2023. Keytruda is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside of the United States and Canada).

PFE Free Cash Flow

Pfizer Inc generated $9.07B in trailing twelve-month free cash flow, representing an FCF yield of 5.98%. This strong FCF yield suggests the company generates substantial cash relative to its market value.

PFE Shares Outstanding

Pfizer Inc has 5.69 billion shares outstanding at a share price of $26.67, giving it a market capitalization of $151.64B.